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Hiroshi Senoo, Ph.D.

Hiroshi Senoo, Ph.D.

Postdoctoral Fellow
Current lab: 
Iijima Lab
Associated Faculty: 
Selected Publications:
Senoo H, Kamimura K, Kimura R, Nakajima A, Sawai S, Sesaki H, Iijima M. 2019. Phosphorylated Rho-GDP Directly Activates mTORC2 Kinase Toward AKT Through Dimerization with Ras-GTP to Regulate Cell Migration. Nature Cell Biology. In press.  
Senoo H, Cai H, Wang Y, Sesaki H, Iijima M. The novel racE binding protein GflB sharpens ras activity at the leading edge of migrating cells. Mol Biol Cell. 2016;27(10):1596-605.
Senoo H, Sesaki H, Iijima M. A GPCR handles bacterial sensing in chemotaxis and phagocytosis. Dev Cell. 2016;36:354-356.
Senoo, H. and Iijima, M. Rho GTPase: a molecular compass for directional cell migration. Commun. Integr. Biol. (2014). Epub ahead of print
Nguyen, H-N., Afkari, Y., Senoo, H., Sesaki, H., Devreotes, P.N. and Iijima, M. (2013). Mechanism of human PTEN localization revealed by heterologous expression in Dictyostelium. Oncogene, Dec. 2. Doi: 10.1038/onc.2013.507. [Epub ahead of print]. PMID:24292679. PMCID: PMC4041858 [Available on 2015/6/2]
Wang, Y., Senoo, H., Sesaki, H. and Iijima, M. Rho GTPases orient gradient sensing in chemotaxis. Proc. Natl. Acad. Sci. USA. (2013). 110: E4723-32.