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Publications

2015

Machamer, C.E. 2015. The Golgi complex in stress and death. Front. Neurosci. 9:421. PMCID: PMC4635215    
Huang C-H and Devreotes PN. 2015. Reaction diffusion waves of phosphoinositides in the membrane. ASBMB TODAY September 2015, Lipid News.  
Westerbeck, J.W. and C.E. Machamer. 2015. A coronavirus E protein is present in two distinct pools with different effects on assembly and the secretory pathway. J. Virol. 2015 Sep;89(18):9313-23.
Hanlon, C.D. and Andrew, D.J. (2015) Outside-in signaling - a brief review of GPCR signaling with a focus on the Drosophila GPCR family. J Cell Sci 128: 3533-3542. PMID:  26345366.
Potapova TA, Unruh JR, Box AC, Bradford WD, Seidel CW, Slaughter BD, Sivagnanam S, Wu Y, Li RKaryotyping human and mouse cells using probes from single-sorted chromosomes and open source software. Biotechniques. 2015 Dec 1;59(6):335-46. doi: 10.2144/000114362. eCollection 2015.
Garcia-Gonzalo FR, Phua SC, Roberson EC, Garcia G 3rd, Abedin M, Schurmans S, Inoue T, Reiter JF. Phosphoinositides regulate ciliary protein trafficking to modulate hedgedog signaling. Dev Cell. 2015 Aug 24;34(4):400-9.
Genin EC, Plutino M, Bannwarth S, Villa E, Cisneros-Barroso E, Roy M, Ortega-Vila B, Fragaki K, Lespinasse F, Pinero-Martos E, Augé G, Moore D, Burté F, Lacas-Gervais S, Kageyama Y, Itoh K, Yu-Wai-Man P, Sesaki H, Ricci JE, Vives-Bauza C, Paquis-Flucklinger V. CHCHD10 mutations promote loss of mitochondrial cristae junctions with impaired mitochondrial genome maintenance and inhibition of apoptosis. EMBO Mol Med. 2015;8:58-72
Fox, R.M. and Andrew, D.J. (2015) Transcriptional regulation of secretory capacity by bZip transcription factors.  Front Biol 10: 28-51.  PMID:  25821458
Nguyen H-N, Yang J-M, Miyamoto T, Itoh K, Rho E, Zhang Q, Inoue T, Devreotes PN, Sesaki H, and Iijima M. 2015. Opening the conformation is a master switch for the dual localization and phosphatase activity of PTEN.  Sci Rep Jul 28;5:12600. doi: 10.1038/srep12600. PMCID: PMC4517176.
Hasan, S., Hétié, P., and Matunis, E.L. (2015). Niche signaling promotes stem cell survival in the Drosophila testis via the JAK-STAT target DIAP1. Dev Biol 404, 27-39.
Santhanam B, Cai H, Devreotes PN, Shaulsky G, and Katoh-Kurasawa M. 2015. The GATA transcription factor GtaC regulates early developmental gene expression dynamics in Dictyostelium.  Nat Commun. Jul6;6:7551. doi: 10.1038/ncomms8551. PMCID: PMC4506546.
Mohan K, Luo T, Robinson DN, Iglesias PA. Cell shape regulation through mechanosensory feedback control. J. R. Soc. Interface. In press.
Zhu J, Heinecke D, Mulla W, Bradford WD, Rubinstein B, Box A, Haug JS and Li R.  Single-cell based quantitative assay of chromosome transmission fidelity. G3. 2015;5:1043-56
Swaney K.F., Borleis J., Iglesias P.A., and Devreotes, P.N. 2015.  Novel protein Callipygian defines the back of migrating cells. PNAS 2015 Jun 30. pii:201509098. [Epub ahead of print]
Loganathan, R., Cheng, Y.L. and Andrew, D.J. (2015) ­Development of the Drosophila Respiratory System.  In:  Organogenetics.  Springer.  In press.
Mojica SA, Hovis KM, Frieman MB, Tran B, Hsia RC, Ravel J, Jenkins-Houk C, Wilson KL, Bavoil PM (2015) SINC, a type III secreted protein of Chlamydia psittaci, targets the inner nuclear membrane of infected cells and uninfected neighbors. Molecular Biology of the Cell 26:1918-1934.
Raychaudhuri s, Espenshade PJ. 2015. Endoplasmic Reticulum Exit of Golgi-resident Defective for SREBP Cleavage (Dsc) E3 Ligase Complex Requires Its Activity. J. Biol. Chem. 290:14430-40.
Gong X, Li J, Shao W, Wu J, Qian H, Ren R, Espenshade PJ*, Nieng Y*. 2015. Crystal structure of the WD40 domain of SCAP from fission yeast reveals the molecular basis for SREBP recognition. Cell Research 25:401-11. PMCID: PMC4387560  
Hoeller O, Toettcher J, Cai H, Devreotes PN, and Weiner O.  Gβ tunes excitability of the actin cytoskeleton to support cell polarity.  PLOS Biology. In press.
Andrew, D.J. and Yelon, D. (2015) Developmental mechanisms, patterning and organogenesisis. Curr Opin Genet Dev. Epub 2015 Jun 4.
Nguyen-Ngoc KV, Shamir ER, Huebner RJ, Beck JN, Cheung KJ, Ewald AJ, “3D Culture Assays of Murine Mammary Branching Morphogenesis and Epithelial Invasion,” Methods Mol Biol. 2015;1189:135-62.
Chen G, Mulla WA, Kucharavy A, Tsai HJ, Rubinstein B, Conkright J, McCroskey S, Bradford WD, Weems L, Haug JS, Seidel CW, Berman J, Li R. Targeting the Adaptability of Heterogeneous Aneuploids. Cell. 2015;160:771-784. 
Gao R, Zhao S, Sun Y, Sanjun Zhao, Gao J, Borleis J, Willard S, Tang M, Cai H, Kamimura Y, Huang Y, Jiang J, Huang Z, Mogilner A, Pan T, Devreotes PN, Zhao M.  2015.  A large-scale screen reveals genes that mediate electrotaxis in Dictyostelium Discoideum.  Sci Signal, May 26;8(378):ra50. Doi: 10.1126/scisignal.aab0562.  PMID: 26012633
Yang J-M, Nguyen H-N, Sesaki H, Devreotes PN, Iijima M. 2015. Engineering PTEN function: Membrane association and activity.  Methods. 2015 May; 0:119-124. PMCID: PMC4388803
Shamir ER and Ewald AJ, “Adhesion in mammary development: novel roles for E-cadherin in individual and collective cell migration,” Curr Top Dev Biol. 2015;112:353-82.
Roy, M., Reddy, P.H., Iijima, M., and Sesaki, H. (2015). Mitochondrial division and fusion in metabolism. Curr. Opin. Cell Biol. 33:111-118
Suraneni P, Fogelson B, Rubinstein B, Noguera P, Volkmann N, Hanein D, Mogilner A, Li R. A Mechanism of Leading Edge Protrusion in the absence of Arp2/3 Complex. Mol Biol Cell. 2015;26:901-12. 
Miyamoto T., Rho E, Sample V., Akano H., Magari M., Ueno T., Chen M., Tokumitsu H., Zhang J., and Inoue T.* “Compartmentalized AMPK Signaling Illuminated by Genetically Encoded Molecular Sensors and Actuators” (Accepted at Cell Reports)
Lin B., Yin T., Wu Y.I., Inoue T.* and Levchenko A.* “Interplay between chemotaxis and contact inhibition of locomotion determines exploratory cell migration” (Accepted at Nature Communications)
McGinnis L, Lee H, Robinson DN, Evans JP. MAPK3/1 (ERK1/2) and myosin light chain kinase in mammalian eggs affect myosin-II function and regulate the metaphase II state in a calcium- and zinc-dependent manner. Biol. Reprod. 2015; In press.
Fox, R.M. and Andrew, D.J. (2015) Changes in organelle position and epithelial architecture associated with loss of CrebA.  Biology Open 4: 317-330.
Shields, L., Kim, H., Zhu, L., Haddad, D., Berthet, A., Pathak, D., Lam, M., Ponnusamy, R., Diaz-Ramirez, L., Gill, T., Sesaki, H., Mucke, L., and Nakamura, K. (2015). Dynamin-related protein 1 is required for normal mitochondrial bioenergetic and synaptic function in CA1 hippocampal neurons. Cell Death Dis. Epub ahead of print. 
Roy M, Kageyama Y, Iijima M, and Sesaki H. PARK2/Parkin becomes critical when DNM1L/Drp1 is absent. Autophagy 2015 Feb. 25 [Epub ahead of print].
Serasinghe, M.N., Weider, S.Y., Renault, T.T., Elkholi, R., Asciolla, J.J., Yao, J.L., Jabado, O., Hoehn, K., Kageyama, Y., Sesaki, H., and Chipuk, J.E. (2015). Mitochondrial division is requisite to RAS-induced transformation and targeted by oncogenic MAPK pathway inhibitors. Mol. Cell. 57: 521-536.
Li, S., Xu, S., Roelofs, B.A., Boyman, L., Lederer, J.W., Sesaki, H., and Karbowski, M. (2015). Transient assembly of F-actin on the outer mitochondrial membrane contributes to mitochondrial fission. J. Cell Biol. 208: 109-123. 
Wang, L., Yu, T., Lee, H., O’Brien, D.K., Sesaki, H., and Yoon, Y. (2015). Decreasing mitochondrial fission diminishes vascular smooth muscle cell migration and ameliorates intimal hyperplasia. Cardiovasc. Res. 106: 272-283.  
Kim JH, Ren Y, Ng WP, Li S, Son S, Kee Y-S, Zhang S, Zhang G, Fletcher DA, Robinson DN, Chen EH. Mechanical tension drives cell membrane fusion. Dev. Cell 2015; 561-573. 
Srivastava V, Robinson DN. Mechanical stress and network structure drive protein dynamics during cytokinesis. Curr. Biol. 2015; 25(5): 663-670. 
Surcel A, Ng W-P, West-Foyle H, Zhu Q, Ren Y, Avery L, Krenc AK, Meyers D, Rock RS, Anders RA, Freel Meyers C, Robinson DN*. Pharmacological activation of myosin II paralogs to correct cell mechanics defects. Proc. Natl. Acad. Sci. USA 2015; 112(5): 1428-1433. 
Luo T, Robinson DN. Kinetic Monte Carlo simulations of the assembly of filamentous biomacromolecules by the dimer addition mechanism. RSC Adv. 2015; 5: 3922-3929.

2014

Chapiro J, Sur S, Savic LJ, Ganapathy-Kniappan S, Reyes J, Duran R, Chettiar-Thiruganasambandam S, Moats CR, Lin M, Luo W, Tran PT, Herman JM, Semenza GL, Ewald AJ, Vogelstein B, Geschwind JF, “Systemic delivery of microencapsulated 2-bromopyruvate for the therapy of pancreatic cancer, Clinical Cancer Research 2014 Dec 15;20(24):6406-17.
Chapiro J, Sur S, Savic LJ, Ganapathy-Kniappan S, Reyes J, Duran R, Chettiar-Thiruganasambandam S, Moats CR, Lin M, Luo W, Tran PT, Herman JM, Semenza GL, Ewald AJ, Vogelstein B, Geschwind JF, “Systemic delivery of microencapsulated 2-bromopyruvate for the therapy of pancreatic cancer," Clinical Cancer Research 2014 Dec 15;20(24):6406-17.
Zhou C, Slaughter BD, Unruh JR, Guo F, Yu Z, Mickey K, Narkar A, Ross RT, McClain M, Li R. Organelle-based aggregation and retention of damaged proteins in asymmetrically dividing cells. Cell. 2014;159:530-542.   
Tong Z, Kim MS, Pandey A, Espenshade PJ. 2014. Identification of candidate substrates for the Golgi Tul1 E3 ligase using quantitative diGly proteomics in yeast. Mol. Cell Proteomics 13:2871-82. PMCID: PMC4223478
Stine, R.R., Greenspan, L.J., Ramachandran, K.V., and Matunis, E.L. (2014). Coordinate regulation of stem cell competition by Slit-Robo and JAK-STAT signaling in the Drosophila testis. PLoS Genet 10, e1004713.
Wang M, Artemenko Y, Cai W, Iglesias PA and Peter N. Devreotes. (2014). The Directional Response of Chemotactic Cells Depends on a Balance between Cytoskeletal Architecture and the External Gradient.  Cell Rep Nov 6;9(3):1110-21. doi: 10.1016/j.celrep.2014.09.047. Epub 2014 Oct 23. PMID: 25437564 [PubMed - in process]. PMCID:PMC4250826  
Ma, Q., Wawersik, M., Matunis, EL.  2014.  The Jak-STAT target Chinmo prevents sex transformation of adult stem cells in the Drosophila testis niche. Dev Cell 31, 474-486.  
Cheung KJ and Ewald AJ, “Illuminating breast cancer invasion: diverse roles for cell-cell interactions”, Current Opinion in Cell Biology, 2014, Oct; 30:99-111.
Kageyama, Y., Hoshijima, M., Seo, K., Bedja, D., Sysa-Shah, P., Andrabi, S., Chen, W., Höke, A., Dawson, V.L., Dawson, T.M., Gabrielson, K., Kass, D.A., Iijima, M., and Sesaki, H. (2014). Parkin-independent mitophagy requires Drp1 and maintains the integrity of mammalian heart and brain. EMBO J. 33: 2798-2813.
Tang M, Wang M, Shi C, Iglesias PA, Devreotes PN, and Huang CH  (2014).  Evolutionarily conserved coupling of adaptive and excitable networks mediates eukaryotic chemotaxis. Nat Commun. Oct 27;5:5175. PMCID: PMC4211273 [Available on 2015/4/27)]
Bryant DM, Roignot J, Datta A, Orvereem A, Kim M, Yu W, Peng X, Eastburn D, Ewald AJ, Werb Z, and Mostov K, “A molecular switch for the orientation of epithelial cell polarization,” Dev Cell, 2014 Oct 27;31(2):171-87.
Bryant DM, Roignot J, Datta A, Orvereem A, Kim M, Yu W, Peng X, Eastburn D, Ewald AJ, Werb Z, and Mostov K, “A molecular switch for the orientation of epithelial cell polarization,” Dev Cell, 2014 Oct 27;31(2):171-87.
Yang JM, Nguyen HN, Sesaki H, Devreotes PN, and Iijima M. 2014.  Engineering PTEN function: Membrane association and activity.  Methods Oct 22. pii: S1046-2023(14)00335-1. doi: 10.1016/j.ymeth.2014.10.018. [Epub ahead of print]. PMID: 25448479
Kageyama, Y., Hoshijima, M., Seo, K., Bedja, D., Sysa-Shah, P., Andrabi, S., Chen, W., Höke, A., Dawson, V.L., Dawson, T.M., Gabrielson, K., Kass, D.A., Iijima, M., and Sesaki, H. (2014). Parkin-independent mitophagy requires Drp1 and maintains the integrity of mammalian heart and brain. EMBO J. 33: 2798-2813.
Shamir ER and Ewald AJ, “3D Organotypic Culture: Experimental Models of Mammalian Biology and Disease,” Nature Reviews Molecular Cell Biology, 2014 Oct;15(10):647-64.
Ren Y, West-Foyle H, Surcel A, Miller C, Robinson DN. Genetic suppression of a phosphomimic myosin II identifies system-level factors promoting myosin II cleavage furrow accumulation. Mol. Biol. Cell. 2014; 25: 4150-4165.
Berthet, A., Margolis, E.B., Zhang, J., Hsieh, I., Zhang, J., Hnasko, T.S., Ahmad, J., Edwards, R.H., Sesaki, H., Huang, E.J., and Nakamura K. (2014). Loss of mitochondrial fission depletes axonal mitochondria in midbrain dopamine neurons. J. Neurosci. 34: 14304-14317.
Bannwarth, S., Ait-El-Mkadem, S., Chaussenot, A., Genin, E.C., Lacas-Gervais, S., Fragaki, K., Berg-Alonso, L., Kageyama, Y., Serre, V., Moore, D., Verschueren, A., Rouzier, A., Le Ber, I., Augé, G., Cochaud, C., Lespinasse, F., N’Guyen, K., Yu Wai Man, P., Sesaki, H., Pouget, J., Paquis-Flucklingerm V. (2014). A mitochondrial origin for frontotemporal dementia and amyotrophic lateral sclerosis through CHCHD10 involvement. Brain. 137: 2329-2345.
Guo, X., Sesaki, H., and Qi, X. (2014). Drp1 stabilizes p53 on the mitochondria to trigger necrosis under oxidative stress conditions, in vitro and in vivo. Biochem. J. 461: 137-146.
Berk JM, Simon DN, Jenkins-Houk CR, Westerbeck JW, Gronning-Wang LM, Carlson CR, Wilson KL (2014) The molecular basis of emerin-emerin and emerin-BAF interactions. J. Cell Science 127:3956-3969. 
Li, Y., Ma, Q., Cherry, C.M., and Matunis, E.L. (2014). Steroid signaling promotes stem cell maintenance in the Drosophila testis. Dev Biol 394, 129-141.
Fox, R.M. and Andrew, D.J. (2014) Transcriptional regulation of secretory capacity by bZip transcripton factors.  Frontiers in Biology 10.1007/s11515-014-1338-7 DOI
Watanabe, S., M.W. Davis, and E.M. Jorgensen. 2014. Flash-and-freeze electron microscopy: coupling optogenetics with high-pressure freezing. In Imaging nanoscale dynamics at synapses. Ed. V. Nägerl and A. Triller. Springer Verlag. Neuromethods 84, p43-57. Book chapter.
Macdonald, P.J., Stepanyants, N., Mehrotra, N., Mears, J.A., Qi, X., Sesaki, H., and Ramachandran, R. (2014). A dimeric equilibrium intermediate nucleates Drp1 reassembly on mitochondrial membranes for fission. Mol. Biol. Cell. 25: 1905-1915.
Watanabe, S., T. Trimbuch, M. Camacho-Pérez, B.R. Rost, B. Brokowski, B. Söhl-Kielczynski, A. Felies, M.W. Davis, C. Rosenmund, and E.M. Jorgensen. 2014. Clathrin regenerates synaptic vesicles from edosomes. Nature 515, p228-33,  DOI 10.1038/nature13846. PMCID: PMC4291189.
Watanabe,  S., M. Lehmann, E. Hujber, R.D. Fetter, J. Richards, B. Söhl-Kielczynski, A. Felies, C. Rosenmund, J. Schmoranzer, and E.M. Jorgensen.  2014. Nanometer-resolution fluorescence electron microscopy (nano-fEM) in cultured cells. Ed. J. Kuo. Humana Press. In Methods in Molecular Biology: Electron Microscopy  1117, p. Book chapter.
Nguyen, H-N., Yang, J.M., Rahdar, M., Keniry, M., Swaney KF, Parsons, R., Park, B.H., Sesaki, H., Devreotes, P.N. and Iijima, M. 2014.  A new class of cancer-associated PTEN mutations defined by membrane translocation defects.  Oncogene Sept 29;0. Doi: 10.1038/onc.2014.293. [Epub ahead of print].  PMID: 25263454
Artemenko, Y., Lampert, T.J., Devreotes, P.N. 2014. Moving towards a paradigm: common mechanisms of chemotactic signaling in Dictyostelium and mammalian leukocytes. Cell Mol Life Sci. Oct;71(19):3711-47. doi: 10.1007/s00018-014-1638-8. Epub 2014 May 21. PMCID: PMC4162842  [Available on 2015/10/1]
Sun Q, Luo T, Ren Y, Shirasawa S, Sasazuki T, Cibas ES, Hodgson L, Robinson DN, Overholtzer M. Competition between human cells by entosis. Cell Res. 2014; 24: 1299-1310.
Ewald AJ and Egeblad M, “Sugar Coated Cell Signaling”, Nature. 2014 Jul 17;511(7509):298-9.
Onuma H, Komatsu T, Arita M, Hanaoka K, Ueno T, Terai T, Nagano T, Inoue T.  2014.  Rapidly rendering cells phagocytic through a cell surface display technique and concurrent Rac activation.  Sci Signal.  Jul 15;7(334):rs4. doi: 10.1126/scisignal.2005123.
Huebner RJ and Ewald AJ, “Cellular Foundations of Mammary Tubulogenesis,” Semin Cell Dev Biol. 2014 Jul;31:124-31.
Damarla, M., Parniari, A.R., Johnston, L., Maredia, H. Serebreni, L., Hamdan, O., Sidhaye, V.K., Shimoda, L.A., Myers, A.C., Crow, M.T., Schmidt, E.P., Machamer, C.E., Gaestei, M. Rane, M.J., Kolb, T.M., Kim, B.S., Damico, R.L., and Hassoun, P.M. (2014) MK2 mediates apoptosis during lung vascular permeability by regulating movement of cleaved caspase 3. Am. J. Respir. Cell Mol. Biol. 50:932-41.
Pulido R, Baker SJ, Barata JT, Carracedo A, Cid VJ, Chin-Sang ID, Davé V, den Hertog J, Devreotes P, Eickholt BJ, Eng C, Furnari FB, Georgescu MM, Gericke A, Hopkins B, Jiang X, Lee SR, Lösche M, Malaney P, Matias-Guiu X, Molina M, Pandolfi PP, Parsons R, Pinton P, Rivas C, Rocha RM, Rodríguez MS, Ross AH, Serrano M, Stambolic V, Stiles B, Suzuki A, Tan SS, Tonks NK, Trotman LC, Wolff N, Woscholski R, Wu H, and Leslie NR. (2014) A unified nomenclature and amino acid numbering for human PTEN. Sci Signal July 1;7(332):pe15. PMID 24985344 [PubMed – as supplied by publisher]
Nguyen HN, Yang JM, Afkari Y, Park BH, Sesaki HDevreotes PN, and Iijima M.  2014.  Engineering ePTEN, an enhanced PTEN with increased tumor suppressor activities. Proc Natl Acad Sci U S A. Jul 1;111(26):E2684-93. PMID: 24979808
Devreotes, P.N. and Horwitz, A.R. Signaling networks that regulate cell migration. In: Cantley, L.C., Hunter, T., Sever, R., Thorner, J. (Eds). 2014.  Signal Transduction.  Principles, Pathways and Processes. Cold Spring Harbor Laboratory Press. Cold Spring Harbor, New York: pp. 183-198.
Chung, S.-Y. and Andrew, D.J. (2014)  Building and specializing epithelial tubular organs:  the Drosophila salivary gland as a model system for revealing how epithelial organs are specified, form and specialize.  Wiley Interdiscip Rev Dev Biol. 3:281-300. PMID: 25208491   
Tamura, Y., Sesaki, H., and Endo, T. (2014). Phospholipid transfer via mitochondria. Traffic. 15: 933-945.
Chung, S.-Y. and Andrew, D.J. (2014) Cadherin 99C regulates apical expansion and cell rearrangement during epithelial tube elongation. Development 141:1950-1960. PMID: 24718992
Suarez A., Ueno T., Huebner R., McCaffery J.M., and Inoue T.* “Bin/Amphiphysin/Rvs (BAR) family members bend membranes in cells” Scientific Reports 4, 4693 (2014)  
Zhang, Q., Tamura, Y., Roy, M., Adachi, Y., and Iijima, M., and Sesaki, H. (2014). Biogenesis and roles of phospholipids in mitochondrial fusion, division and mitophagy. Cell Mol. Life Sci. 71: 3767-3778.
Hetie, P., de Cuevas, M. and Matunis, E.  2014.  Conversion of Quiescent Niche Cells to Somatic Stem Cells Causes Ectopic Niche Formation in the Drosophila Testis. Cell Reports 7, 715-721.
Sesaki, H., Adachi, Y., Kageyama, Y., Itoh, K., and Iijima, M. (2014). In vivo functions of Drp1: Lessons learned from yeast genetics and mouse knockouts. Biochim Biophys Acta. 1842: 1179-1185.
Luo T, Srivastava V, Ren Y, Robinson DN. Mimicking the mechanical properties of the cell cortex by the self-assembly of an actin cortex in vesicles. App. Phys. Lett. 2014; 104: 153701-1-5.
Gilbert, C.E., D.M. Zuckerman, P.L. Currier, and C. E. Machamer. 2014. Three basic residues of intracellular loop 3 of the beta-1 adrenergic receptor are required for golgin-160-dependent trafficking. Int. J. Mol. Sci.15:2929-45.  
Cheung KJ and Ewald AJ, “Invasive leader cells: metastatic oncotarget,” Oncotarget. 2014 Mar 30;5(6):1390-1.
Mulla W, Zhu J, Li R. Yeast: a simple model system to study complex phenomena of aneuploidy. FEMS Microbiol Rev. 2014 Mar;38(2):201-12. doi: 10.1111/1574-6976.12048. Epub 2013 Oct 31. Review. PMID:24118136.
Cai H, Katoh-Kurasawa M, Muramoto T, Santhanam B, Long Y, Li L, Ueda M, Iglesias PA, Shaulsky G, and Devreotes PN. Nucleocytoplasmic shuttling of a GATA transcription factor functions as a development timer. Science. 2014 Mar 21;343(6177):1249531. doi: 10.1126/science.1249531.
Shao W, Espenshade PJ. 2014. Sterol Regulatory Element-binding Protein (SREBP) cleavage regulates Golgi-to-Endoplasmic Reticulum recycling of SREBP Cleavage-activating Protein (SCAP). J. Biol. Chem. 289:7547-7557.
Guo X., Sesaki H., and Qi X. (2014). Drp1 stabilizes p53 on the mitochondria to trigger necrosis under oxidative stress conditions, in vitro and in vivo. Biochem. J. 461: 137-146.
Brookheart RT, Lee CY, Espenshade PJ. 2014. Casein kinase 1 regulates sterol regulatory element- binding protein (SREBP) to control sterol homeostasis. J. Biol. Chem. 289:2725-2735.
Huebner RJ, Lechler T, Ewald AJ, “Mammary epithelial stratification occurs through symmetry breaking vertical divisions of luminal cells,” Development. 2014 Mar;141(5):1085-94
Shamir ER, Papallardo E, Jorgens DM, Coutinho K, Tsai WT, Aziz K, Auer M, Tran PT, Bader JS, Ewald AJ, “Twist1-induced dissemination preserves epithelial identity and requires E-cadherin,” JCB 2014 Mar 3;204(5):839-56 (Selected for cover). 
Huebner RJ, Lechler T, Ewald AJ, “Mammary epithelial stratification occurs through symmetry breaking vertical divisions of luminal cells,” Development. 2014 Mar;141(5):1085-94. 
Chen Q, Zhang N, Gray RS, Li H, Ewald AJ, Zahnow CA, and Pan DJ, A temporal requirement for Hippo signaling in mammary gland differentiation, growth and tumorigenesis, Genes Dev. 2014 Mar 1;28(5):432-7. doi: 10.1101/gad.233676.113.
Yang, Z., Grinchuk, V., Smith, A., Qin, B., Bohl, J., Sun, R., Notari, L., Zhang, Z., Sesaki, H., Urban, J., Shea-Donohue, T., and Zhao, A. (2014). Parasitic nematode-induced modulation of body weight and associated metabolic dysfunction in mouse models of obesity. Infection and Immunity. 81: 1905-1914
Chen Q, Zhang N, Gray RS, Li H, Ewald AJ, Zahnow CA, and Pan DJ, A temporal requirement for Hippo signaling in mammary gland differentiation, growth and tumorigenesis, Genes Dev. 2014 Mar 1;28(5):432-7.
Chen Q, Zhang N, Gray RS, Li H, Ewald AJ, Zahnow CA, and Pan DJ, “A temporal requirement for Hippo signaling in mammary gland differentiation, growth and tumorigenesis”, Genes Dev. 2014 Mar 1;28(5):432-7.
Senoo, H. and Iijima, M. Rho GTPase: a molecular compass for directional cell migration. Commun. Integr. Biol. (2014). Epub ahead of print

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