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Recent Publications

A listing of publications from the last 12 months...

2018

Sisk, J.M., M.B. Frieman and C.E. Machamer. 2018. Coronavirus S protein-induced fusion is blocked prior to hemifusion by Abl kinase inhibitors. J. Gen. Virol., Mar 20. doi: 10.1099/jgv.0.001047. [Epub ahead of print]
Gilbert, C.E., E. Sztul and C.E. Machamer. 2018. Commonly used trafficking blocks disrupt ARF1 activation and the localization and function of specific Golgi proteins. Molec. Biol. Cell, E17-11-0622. doi: 10.1091/mbc.E17-11-0622. [Epub ahead of print]  
Edwards M, Cai H, Abubaker-Sharif  B, Long Y, Lampert T, and Devreotes PN. 2018. Insight from the maximal activation of the signal transduction excitable network in Dictyostelium discoideum. Proc Natl Acad Sci USA. March 30, 018. 201710480; published ahead of print March 30, 2018.  

2017

Thomas DG, Robinson DN. 2017. The fifth sense: Mechanosensory regulation of alpha-actinin-4 and its relevance for cancer metastasis. Sem. Cell Dev. Biol. 2017; 71: 68-74.
Nishida K, Brune KA, Putcha N, Mandke P, O’Neal WK, Shade D, Srivastava V, Wang M, An SS, Drummond MB, Hansel NN, Robinson DN, Sidhaye V.  2017. Cigarette smoke disrupts monolayer integrity by altering epithelial cell-cell adhesion and cortical tension. Am. J. Physiol. – Lung Cell Mol. Physiol. 2017; 313(3): L581-L591.
Miao C, Schiffhauer ES, Okeke E, Robinson DN, Luo T. 2017. Parallel compression is a fast, low-cost assay for the high throughput screening of mechanosensory cytoskeletal proteins in cells. ACS Appl. Mater. Interfaces 2017; 9(34): 28168-28179. ACS Appl. Mater. Interfaces 2017; 9(34): 28168-28179
Duan R, Kim JH, Shilagardi K, Schiffhauer E, Son S, Lee D, Li S, Thomas C, Luo T, Fletcher DA, Robinson DN, Chen EH. Spectrin is mechanoresponsive protein shaping the architecture of intercellular invasion. bioRxiv; DOI: 10.1101/154831  
Nakamura H, Lee AA, Afshar AS, Lin YC, Tanigawa M, Suarez A, Razavi S, DeRose R, Bobb D, Hong W, Gabelli SB, Goutsias J, Inoue T. 2017. Intracellular production of hydrogels and synthetic RNA granules by multivalent molecular interactions. Nature Materials (In press, doi:10.1038/nmat5006)  
Dharmaraj T and Wilson KL. (2017). How chromosomes unite. Nature 551:568-569.
Mulla WA, Seidel CW, Zhu J, Tsai HJ, Smith SE, Singh P, Bradford WD, McCroskey S, Nelliat AR, Conkright J, Peak A, Malanowski KE, Perera AG, Li R. 2017. Aneuploidy as a cause of impaired chromatin silencing and mating-type specification in budding yeast. Elife. 2017 Aug 25; 6. pii: e27991. doi: 10.7554/eLife.27991.
McDonald NALind ALSmith SELi RGould KL. 2017.  Nanoscale architecture of the Schizosaccharomyces pombe contractile ring. Elife. 2017 Sep 15; 6. pii: e28865. doi: 10.7554/eLife.28865.
Anderson KL, Page C, Swift MF, Suraneni P, Janssen MEW, Pollard TD, Li R, Volkmann N, Hanein D. 2017. Nano-scale actin-network characterization of fibroblast cells lacking functional Arp23 complex. Journal of structural biology, 197 (3) 312-321.
Scherer PC, Zaccor NW, Neumann NM, Vasavda C, Barrow R, Ewald AJ, Rao F, Sumner CJ, Snyder SH. 2017. TRPV1 is a physiological regulator of μ-opioid receptors. Proc Natl Acad Sci U S A. 2017 Dec 4. pii: 201717005. doi: 10.1073/pnas.1717005114. [Epub ahead of print]
Artemenko, Y., Devreotes, P. N. Assessment of Dictyostelium discoideum Response to Acute Mechanical Stimulation. J. Vis. Exp.(129), e56411, doi:10.3791/56411 (2017).
Asrani K, Sood A, Torres A, Georgess D, Phatak P, Kaur H, Dubin A, Talbot CC Jr, Elhelu L, Ewald AJ, Xiao B, Worley P, Lotan TL. 2017. mTORC1 loss impairs epidermal adhesion via TGF-β/Rho kinase activation. J Clin Invest. 2017 Nov 1;127(11):4001-4017. doi: 10.1172/JCI92893. Epub 2017 Sep 25.
Surcel A, Schiffhauer ES, Thomas D, Zhu Q, DiNapoli K, Herbig M, Otto O, Guck J, Jaffee E, Iglesias P, Anders R, Robinson DN. Harnessing the adaptive potential of mechanoresponsive proteins to overwhelm pancreatic cancer dissemination and invasion. bioRxiv 190553; doi: https://doi.org/10.1101/190553. 2017
Hamann JC, Surcel A, Chen R, Teragawa C, Albeck JG, Robinson DN, Overholtzer M. Entosis is induced by glucose starvation. Cell Reports. 20(1): 201-210. 2017
Kameoka S, Adachi Y, Okamoto K, Iijima M, Sesaki H. 2017. Phosphatidic Acid and Cardiolipin Coordinate Mitochondrial Dynamics. Trends Cell Biol. [Epub ahead of print].
Devreotes PN, Bhattacharya S, Edwards M, Iglesias PA, Lampert T, Miao Y. 2017. Excitable Signal Transduction Networks in Directed Cell Migration. Annu Rev Cell Dev Biol Oct. 6;33:103-125. Doi: 10.1146/annurev-cellbio-100616-060739. PMID: 28793794
Gerber S, Charif M, Chevrollier A, Chaumette T, Angebault C, Kane MS, Paris A, Alban J, Quiles M, Delettre C, Bonneau D, Procaccio V, Amati-Bonneau P, Reynier P, Leruez S, Calmon R, Boddaert N, Funalot B, Rio M, Bouccara D, Meunier I, Sesaki H, Kaplan J, Hamel CP, Rozet JM, Lenaers G. 2017. Mutations in DNM1L, as in OPA1, result indominant optic atrophy despite opposite effectson mitochondrial fusion and fission. Brain. 140(10):2586-2596. 
Yochum ZA, Cades J, Mazzacurati L, Neumann NM, Khetarpal SK, Chatterjee S, Wang H, Attar MA, Huang EH, Chatley SN, Nugent K, Somasundaram A, Engh JA, Ewald AJ, Cho YJ, Rudin CM, Tran PT, Burns TF. 2017. A First-in-Class TWIST1 Inhibitor with Activity in Oncogene-Driven Lung Cancer. Mol Cancer Res. 2017 Dec;15(12):1764-1776. doi: 10.1158/1541-7786.MCR-17-0298. Epub 2017 Aug 29.
Lampert TJ, Kamprad N, Edwards M, Borleis J, Watson AJ, Tarantola M, Devreotes PN.  2017. Shear force-based genetic screen reveals negative regulators of cell adhesion and protrusive activity. Proc Natl Acad Sci USA Aug 28. Pii: 201616600. Doi: 10.1073/pnas.1616600114. [Epub ahead of print]. PMCID: PMC5603988
Nguyen-Ngoc KV, Silvestri VL, Georgess D, Fairchild AN, Ewald AJ. 2017. Mosaic loss of non-muscle myosin IIA and IIB is sufficient to induce mammary epithelial proliferation. J Cell Sci. 2017 Oct 1;130(19):3213-3221. doi: 10.1242/jcs.208546. Epub 2017 Aug 18.
Greenspan LJ, Matunis EL. 2017. Live Imaging of the Drosophila Testis Stem Cell Niche. Methods Mol Biol. 1463:63-74.
Burr R, Stewart EV, Espenshade PJ. 2017. Coordinate regulation of yeast Sterol Regulatory Element-binding Protein (SREBP) and Mga2 transcription factors. J. Biol. Chem. 292:5311-5324. PMCID: PMC5392677
Adachi Y, Itoh K, Iijima M, Sesaki H. 2017. Assay to measure interactions between purified Drp1 and synthetic liposomes. Bio-Protocol. Vol 7, Iss 9.
Santoro A, Campolo M, Liu C, Sesaki H, Meli R, Liu ZW, Kim JD, Diano S. 2017. DRP1 Suppresses Leptin and Glucose Sensing of POMC Neurons. Cell Metab. 25(3):647-660.  
Bordt EA, Clerc P, Roelofs BA, Saladino AJ, Tretter L, Adam-Vizi V, Cherok E, Khalil A, Yadava N, Ge SX, Francis TC, Kennedy NW, Picton LK, Kumar T, Uppuluri S, Miller AM, Itoh K, Karbowski M, Sesaki H, Hill RB, Polster BM. 2017. The putative Drp1 inhibitor mdivi-1 Is a reversible mitochondrial complex I inhibitor that modulates reactive oxygen species. Dev Cell. 2017;40(6):583-594.
Adachi Y, Iijima M, Sesaki H. An unstructured loop that is critical for interactions of the stalk domain of Drp1 with saturated phosphatidic acid.  2017 Jun 23:1-8. doi: 10.1080/21541248.2017.1321614. [Epub ahead of print]
Florwick A, Dharmaraj T, Jurgens J, Valle D, Wilson KL. 2017.  LMNA sequences of 60,706 unrelated individuals reveal 132 novel missense variants in A-type lamins and suggest a link between variant p.G602S and Type 2 Diabetes.  Jun 15;8:79. doi: 10.3389/fgene.2017.00079. eCollection 2017.
Pereira R, Tadinada SM, Zasadny FM, Oliveira K, Pires KM, Olvera A, Jeffers J, Souvenir R, Mcglauflin R, Seei A, Funari T, Sesaki H, Potthoff MJ, Adams CM, Anderson EJ, Abel ED. 2017. OPA1 deficiency promotes secretion of FGF21 from muscle that prevents obesity and insulin resistance.  2017 Jun 12. pii: e201696179. doi: 10.15252/embj.201696179. [Epub ahead of print]
Cho B, Cho HM, Jo MY, Kim HD, Song M, Moon C, Kim H, Kim K, Sesaki H, Rhyu IJ, Kim H. Constriction of the mitochondrial inner compartment is a priming event for mitochondrial division.  2017 Jun 9;8:15754. doi: 10.1038/ncomms15754.  
Watanabe S. and Boucrot E. (2017) Fast and ultrafast endocytosis. Curr Opin Cell Biol. 5;47:64-71.
Topalidou I, Chen PA, Cooper K, Watanabe S, Jorgensen EM, Ailion M. (2017). The NCA-1 and NCA-2 Ion Channels Function Downstream of Gq and Rho To Regulate Locomotion in Caenorhabditis elegans. Genetics May;206(1):265-282.
Schiffhauer E, Robinson DN. 2017. Mechanochemical signaling directs cell shape change. Biophys. J. 112: 207-214. (Featured article)
Kothari P, Schiffhauer E, Robinson DN. Cytokinesis from nanometers to micrometers and microseconds to minutes. 2017. Methods Cell Biol. 137:307-322.
Yamada T, Adachi Y, Yanagawa T, Iijima M, Sesaki H. 2017. p62/sequestosome-1 knockout delays neurodegeneration induced by Drp1 loss. Neurochem Int. 2017 May 18. pii: S0197-0186(17)30189-4. doi: 10.1016/j.neuint.2017.05.012. [Epub ahead of print]
Rohani A, Moore JH, Kashatus JA, Sesaki H, Kashatus DF, Swami NS. Label-Free Quantification of Intracellular Mitochondrial Dynamics Using Dielectrophoresis. Anal Chem. 2017 Jun 6;89(11):5757-5764. doi: 10.1021/acs.analchem.6b04666. Epub 2017 May 15
Chen Z, Jiang H, Xu W, Li X, Dempsey DR, Zhang X, Devreotes P, Wolberger C, Amzel M, Gabelli SB, Cole PA.  2017. A Tunable Brake for HECT Ubiquitin Ligases. Molecular Cell 66 (3): 345-357. PMID: 28475870. DOI: 10.1016/j.molcel.2017.03.020
Xian L, Georgess D, Huso T, Cope L, Belton A, Chang YT, Kuang W, Zhang X, Senger S, Fassano A, Huso DL, Ewald AJ, Resar LMS. 2017. HMGA1 Amplifies Wnt Signaling and Expands the Intestinal Stem Cell Compartment and Paneth Cell Niche. Nat Communications, 2017 Apr 28;8:15008