Duis autem vel eum iriure dolor in hendrerit.

Recent Publications

A listing of publications from the last 12 months...

2019

Surcel A, Schiffhauer ES, Thomas DG, Zhu Q, DiNapoli K, Herbig M, Otto O, West-Foyle H, Jacobi A, Kräter M, Plak K, Guck J, Jaffee EM, Iglesias PA, Anders RA, Robinson DN. Targeting mechanoresponsive proteins in pancreatic cancer: 4-hydroxyacetophenone blocks dissemination and invasion by activating MYH14. Cancer Res. In press.  
Kothari P, Johnson C, Sandone C, Iglesias PA, Robinson DN. How the mechanobiome drives cell behavior, viewed through the lens of control theory. J. Cell Sci. In press.  
Spear, E.D, Alford, R.F., Babatz, T.D., Wood, K., Mossberg, O.  Shilgardi, K., Odinammadu, K Gray, J., and Michaelis, S. (2019) A Humanized Yeast System to Analyze Cleavage of Prelamin A by ZMPSTE24. Methods 157:47-55
  Nakamura H, DeRose R, Inoue T. “Harnessing biomolecular condensates in living cells” Journal of Biochemistry (in press, 2019)  
Wells, M.B. and Andrew, D.J. (2019) The architecture of the Anopheles stephensi salivary gland presents major barriers to transmission of the malaria parasite Plasmodium berghei.  MBio. In press.
Johnson, D.M. and Andrew, D.J. (2019) Role of tbc1 in Drosophila embryonic salivary glands.  BMC Cell and Molec. Biol  20:19  
Suresh, K., K. Carino, L. Johnston, L. Servinsky, C. Machamer, T. Kolb, H. Lam, S. Dudek, S. An, M. Rane, L. Shimoda, and M. Damarla. 2019. A non-apoptotic, endothelial barrier-protective role for caspase 3. Amer. J. Physiol. Lung 316)6):L1118-L1126. 
Westerbeck, J.W. and C.E. Machamer. 2019. The infectious bronchitis virus coronavirus envelope protein alters Golgi pH to protect spike protein and promote release of infectious virus. J. Virol.93(11):1-15. PMCID: PMC6532078
Padmanaban V, Suhail Y, Bader JS, Ewald AJ, "E-cadherin suppresses invasion and promotes metastasis in multiple breast cancer models," Accepted in Principle at Nature, 2019.  
Adachi Y, Iijima M, Sesaki H. An unstructured loop that is critical for interactions of the stalk domain of Drp1 with saturated phosphatidic acid. Small GTPases. 2018 Nov 2;9(6):472-479.  
Sarbajeet Nagdas, Jennifer A. Kashatus, Aldo Nascimento, Riley E. Trainor, Sarah R. Pollock, Sara J. Adair, Alex D. Michaels, Hiromi Sesaki, Edward B. Stelow, Todd W. Bauer and David F. Kashatus. Drp1 promotes KRas-driven metabolic changes to drive pancreatic tumor growth. Cell Reports. In press  
Yamada T, Dawson TM, Yanagawa T, Iijima M, Sesaki H. SQSTM1/p62 promotes mitochondrial ubiquitination independently of PINK1 and PRKN/parkin in mitophagy. Autophagy. 2019; In press.
Michael P. Catanzaro, Ashley Weiner, Amanda Kaminaris, Fei Cai, Cairong Li, Fengyi Zhao, Satoru Kobayashi, Tamayo Kobayashi, Yuan Huang, Hiromi Sesaki, Qiangrong Liang. Doxorubicin-induced Cardiomyocyte Death is Mediated by Unchecked Mitochondrial Fission and Mitophagy. FASEB J. In press.  
Senoo H, Kamimura K, Kimura R, Nakajima A, Sawai S, Sesaki H, Iijima M. Phosphorylated Rho-GDP directly activates mTORC2 Kinase toward AKT through dimerization with Ras-GTP to regulate cell migration. Nature Cell Biology. 2019; Epub ahead of Print  
Arun A, Eddings CR and Wilson KL (2019) Novel missense alleles of SIGMAR1 as tools to understand emerin-dependent gene silencing in response to cocaine. Exp. Biology & Medicine (in press) 
Surcel A, Robinson DN.* Meddling with myosin’s mechanobiology in cancer. Proc. Natl. Acad. Sci. U.S.A. 2019; In press.    
Andrew, D.J., Chen, E.H., Manoli, D.S., Ryner, L.C. and Arbeitman, M.N. (2019) Sex and the single fly: A perspective on the career of Bruce S. Baker. Genetics 212(2) 365-376
Paul P, Ramachandran S, Xia S, Unruh JR, Conkright-Fincham J, Li R. 2019. Dopamine receptor antagonists as potential therapeutic agents for ADPKD. PLoS One. 2019 May 6;14(5):e0216220. doi: 10.1371/journal.pone.0216220. eCollection 2019  
Tsai H-J, Nelliat AR, Choudhury MI, Kucharavy A, Bradford WD, Cook ME, Kim J, Mair DB, Sun SX, Schatz MC & Li R. 2019. Hypo-osmotic-like stress underlies general cellular defects of aneuploidyNature (2019) https://doi.org/10.1038/s41586-019-1187-2.  
Hickey JW, Dong Y, Chung JW, Salathe SF, Pruitt HC, Li X, Chang C, Fraser AK, Bessell CA, Ewald AJ, Gerecht S, Mao HQ, Schneck JP, " Engineering an Artificial T-Cell Stimulating Matrix for Immunotherapy," Adv Mater. 2019 Apr 10:e1807359. 
Dharmaraj T, Guan YC, Liu J, Badens C, Gaborit B and Wilson KL (2019) Rare BANF1 variants and relatively frequent EMD variants including ‘healthy lipid’ emerin p.D149H in the ExAC cohort. Front. Cell Dev. Biol. 05 April 2019 https://doi.org/10.3389/fcell.2019.00048  
Palma E, Ma X, Riva A, Iansante V, Dhawan A, Wang S, Ni HM, Sesaki H, Williams R, Ding WX, Chokshi S. Dynamin-1-Like Protein Inhibition Drives Megamitochondria Formation as an Adaptive Response in Alcohol-Induced Hepatotoxicity. Am J Pathol. 2019 Mar;189(3):580-589.
Schiffhauer ES, Ren Y, Iglesias V, Kothari P, Iglesias PA, Robinson DN*. Myosin IIB assembly-state determines myosin IIB mechanosensitive dynamics. J. Cell Biol. 2019; 218(3): 895-908. (Includes 4 pages of Supplemental Figures)
Gutiérrez MS, Campusano S, González AM, Gómez M, Barahona S, Sepúlveda D, Espenshade PJ, Fernández-Lobato M, Baeza M, Cifuentes V, Alcaíno J. Sterol Regulatory Element-Binding Protein (Sre1) Promotes the Synthesis of Carotenoids and Sterols in Xanthophyllomyces dendrorhous. Front Microbiol. 2019 Mar 29;10:586. doi: 10.3389/fmicb.2019.00586. eCollection 2019.  
Miao Y, Battacharya S, Banerjee T, Abudaker-Sharif B, Long Y, Inoue T, Iglesias P and Devreotes P. (2019). Wave patterns organize cellular protrusions and control cortical dynamics. Molecular Systems Biology 15(3). DOI 10.15252/msb.20188585| Published online 11.03.2019.
Kothari P, Srivastava V, Aggarwal V, Tchernyshyov I, Van Eyk J, Ha T, and Robinson DN*. Contractility kits promote assembly of the mechanoresponsive cytoskeletal network. J. Cell Sci. 2019; 132(2): 1-12. (Cover article; includes 11 pages of Supplemental Figures and Tables; first author was featured in a “First Person – Priyanka Kothari” interview, J. Cell Sci 2019 132: jcs229195)  
Zhang W, Zhang X, Xue Z, Li Y, Ma Q, Ren X, Zhang J, Yang S, Yang L, Wu M, Ren M, Xi R, Wu Z, Liu JL, Matunis E, Dai J, Gao G. (2019).  Probing the function of metazoan histones with a systematic library of H3 and H4 mutants.  Dev Cell Feb 11;48(3):406-419.
Li L, Knutsdottir H, Hui K, Weiss MJ, He J, Philosophe B, Cameron AM, Wolfgang CL, Pawlik TM, Ghiaur G, Ewald AJ, Mezey E, Bader JS, Selaru FM, "Human primary liver cancer organoids reveal intra-tumor and inter-patient drug response heterogeneity," JCI Insight. 2019 Jan 24;4(2). pii: 121490.    
Schiffhauer ES, Ren Y, Iglesias V, Kothari P, Iglesias PA, Robinson DN. 2019. Myosin IIB assembly-state determines myosin IIB mechanosensitive dynamics. J. Cell Biol. In press.  
Kojima R, Kakimoto Y, Furuta S, Itoh K, Sesaki H, Endo T, Tamura Y. Maintenance of Cardiolipin and Crista Structure Requires Cooperative Functions of Mitochondrial Dynamics and Phospholipid Transport. Cell Rep. 2019 Jan 15;26(3):518-528.  

2018

Wu ZH, Su MH, Tong CS, Wu M, Liu J. 2018. Membrane shape-mediated wave propagation of cortical protein dynamics. Nature Communications 9(1): 136.  
Mair, Devin B., Heather M. Ames, and Rong Li. “Mechanisms of invasion and motility of high-grade gliomas in the brain.” Molecular biology of the cell 29.21 (2018): 2509-2515
Miyanaga Y, Kamimura Y, Kuwayama H, Devreotes PN, and Ueda M. (2018). Chemoattractant receptors activate, recruit and capture G proteins for wide range chemotaxis. Biochemical and Biophysical Research Communications. Nov 16. pii: S0006-291X(18)32435-5. doi: 10.1016/j.bbrc.2018.11.029. [Epub ahead of print] PubMed PMID: 30454895.  
Genin EC, Bannwarth S, Lespinasse F, Ortega-Vila B, Fragaki K, Itoh K, Villa E, Lacas-Gervais S, Jokela M, Auranen M, Ylikallio E, Mauri-Crouzet A, Tyynismaa H, Vihola A, Aug G, Cochaud C, Sesaki H, Ricci JE, Udd B, Vives-Bauza C, Paquis-Flucklinger V. Loss of MICOS complex integrity and mitochondrial damage, but not TDP-43 mitochondrial localisation, are likely associated with severity of CHCHD10-related diseases. Neurobiol Dis. 2018 Nov;119:159-171.