Dr. Antony Rosen was an Osler resident and rheumatology fellow at Johns Hopkins Hospital before joining the faculty at Johns Hopkins, where he was appointed a professor in 2002. He…
Research Topic: Regulation of cell migration by cell-ECM adhesion and integrin signaling
Cell migration is essential for a variety of biological events including embryonic development, wound healing, inflammation and the metastasis…
Research Topic: Signaling, cell-cell interaction, intercellular communication, immune cell activation, multi-dimensional imaging, novel biosensors
The long-term goal of our studies is to understand the complex cellular and molecular mechanisms of…
Research Topic: Trafficking Mechanisms of Copper-ATPases in Polarized Epithelial Cells
Epithelia are an important tissue type in the body, because they form selective barriers between the external and internal environments. Of…
Within each human cell is a NUCLEUS, 'mothership' of the human genome and still the least-understood cellular structure. Chromosomes are enclosed by the nuclear envelope (NE) and communicate with the…
Research Topic: Golgi complex structure/function; intracellular protein trafficking; intracellular virus assembly; coronaviruses; exocytosis of large cargo
We are interested in the structure and function of the Golgi complex, a ubiquitous…
Background and Summary
The Ewald Lab seeks to understand how groups of cells cooperate, compete, and interact to organize tissue architecture and function during development and disease progression. Our foundation is…
Research Summary
Multi-cellular living organisms grow from single cells into multicellular, complex systems composed of highly diverse cell-types organized into tissues, which in turn form organs and organ systems. To organize…
Research Topic : Progeria and lamin A processing by the ZMPSTE24 protease; ERAD and cytosolic protein quality control; yeast and mammalian cell biology.
The overall goal of our research is to…
One of the major challenges in cell biology is to understand how biochemical reactions at the molecular scale self-organize to generate physiological forms and functions at the cellular and tissue…