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Recent Publications

A listing of publications from the last 12 months...

2019

Schiffhauer ES, Ren Y, Iglesias V, Kothari P, Iglesias PA, Robinson DN. 2019. Myosin IIB assembly-state determines myosin IIB mechanosensitive dynamics. J. Cell Biol. In press.  
Kothari P, Srivastava V, Aggarwal V, Tchernyshyov I, Van Eyk J, Ha T, and Robinson DN. 2019. Contractility kits promote assembly of the mechanoresponsive cytoskeletal network. J. Cell Sci. 2019; 132(2): 1-12.  

2018

Wu ZH, Su MH, Tong CS, Wu M, Liu J. 2018. Membrane shape-mediated wave propagation of cortical protein dynamics. Nature Communications 9(1): 136.  
Miyanaga Y, Kamimura Y, Kuwayama H, Devreotes PN, and Ueda M. (2018). Chemoattractant receptors activate, recruit and capture G proteins for wide range chemotaxis. Biochemical and Biophysical Research Communications. Nov 16. pii: S0006-291X(18)32435-5. doi: 10.1016/j.bbrc.2018.11.029. [Epub ahead of print] PubMed PMID: 30454895.  
Li X, Edwards M, Swaney KF, Singh N, Bhattacharya S, Borleis J, Long Y, Iglesias PA, Chen J, and Devreotes PN. 2018. Mutually inhibitory Ras-PI(3,4)P2 feedback loops mediate cell migration. PNAS published ahead of print Sept. 7, 2018. https://doi.org/10.1073/pnas.1809039115
Liu Y and Robinson D. 2018. Recent advances in cytokinesis: Understanding the molecular underpinnings. F1000Research 2018; 7(F1000 Faculty Rev): 1849.  
Yamada T, Murata D, Adachi Y, Itoh K, Kameoka S, Igarashi A, Kato T, Araki Y, Huganir RL, Dawson TM, Yanagawa T, Okamoto K, Iijima M and Sesaki H. (2018). Mitochondrial stasis reveals p62-mediated ubiquitination in parkin-independent mitophagy and mitigates nonalcoholic fatty liver disease. Cell Metabolism. In press.  
Naoto Takada, Tomoki Naito, Inoue T, Kazuhisa Nakayama, Hiroyuki Takatsu, Hye-Won Shin. “Enhanced phospholipid flipping by P4-ATPase promotes membrane deformation.” 2018. EMBO Reports (in press). 
Cuei-Ling Wang, Yu-Chen Chang, Ya-Chu Chang, Shi-Rong Hong, Chun-Yu Lin, Ning Hsu, Hsiao-Chi Cheng, Yueh-Chen Chiang, Wei-En Huang, Nathan C. Shaner, Rajat Rohatgi, Inoue T, Yu-Chun Lin. (2018).“Spatiotemporal manipulation of ciliary glutamylation reveals its roles in intraciliary trafficking and Hedgehog signaling.”Nature Communications 2018:9:1732:1-13
Igarashi, A., Itoh, K., Yamada, T., Adachi, Y., kato, T., Murata, D., Sesaki, H., and Iijima, M. (2018).  Nuclear PTEN deficiency causes microcephaly with decreased neuronal soma size and increased seizure susceptibility. J. Biol. Chem. Accepted.  
Spear E. D,. Hsu E.-T., Nie L., Carpenter E.P., Hrycyna C.A., and Michaelis S. (2018). ZMPSTE24 Missense mutations that cause progeroid diseases decrease prelamin A cleavage activity and/or  protein stability.  Disease Models and Mechanism (Under revision)  
Worman, H. J. and Michaelis, S. (2018). Permanently Farnesylated Prelamin A, Progeria and Atherosclerosis.  Circulation (In Press)  
Preston G. M., Guerriero C. J., Metzger M.B., Michaelis S. and Brodsky J.L. 2018. Substrate insolubility dictates Hsp104-dependent endoplasmic reticulum associated degradation.  Mol. Cell 70:242-253 
Nemani N, Carvalho E, Tomar D, Dong Z, Ketschek A, Breves SL, Jaña F, Worth AM, Heffler J, Palaniappan P, Tripathi A, Subbiah R, Riitano MF, Seelam A, Manfred T, Itoh K, Meng S, Sesaki H, Craigen WJ, Rajan S, Shanmughapriya S, Caplan J, Prosser BL, Gill DL, Stathopulos PB, Gallo G, Chan DC, Mishra P, Madesh M. 2018. MIRO-1 Determines Mitochondrial Shape Transition upon GPCR Activation and Ca2+ Stress. Cell Rep. 2018 Apr 24;23(4):1005-1019.  
Kwon D, Sesaki H, Kang SJ. 2018. Intracellular calcium is a rheostat for the STING signaling pathway. Biochem Biophys Res Commun. 2018 Jun 2;500(2):497-503. doi: 10.1016/j.bbrc.2018.04.117. Epub 2018 Apr 21.  
Jouroukhin Y, Kageyama Y, Misheneva V, Shevelkin A, Andrabi S, Prandovszky E, Yolken RH, Dawson VL, Dawson TM, Aja S, Sesaki H, Pletnikov MV. 2018. DISC1 regulates lactate metabolism in astrocytes: implications for psychiatric disorders. Transl Psychiatry. 2018 Apr 12;8(1):76. doi: 10.1038/s41398-018-0123-9.  
Neumann NM, Perrone MC, Veldhuis JH, Huebner RJ, Zhan H, Devreotes PN, Brodland GW, Ewald AJ. 2018. Coordination of Receptor Tyrosine Kinase Signaling and Interfacial Tension Dynamics Drives Radial Intercalation and Tube Elongation. Dev Cell. 2018 Apr 9;45(1):67-82.e6. doi: 10.1016/j.devcel.2018.03.011. PMID: 29634937  
Roy S, Esmaeilniakooshkghazi A, Patnaik S, Wang Y, George SP, Ahrorov A, Hou JK, Herron AJ, Sesaki H, Khurana S. 2018. Villin-1 and Gelsolin Regulate Changes in Actin Dynamics That Affect Cell Survival Signaling Pathways and Intestinal Inflammation Gastroenterology. 2018 Apr;154(5):1405-1420  
Gajendiran P, Vega LI, Itoh K, Sesaki H, Vakili MR, Lavasanifar A, Hong K, Mezey E, Ganapathy-Kanniappan S. 2018. Elevated mitochondrial activity distinguishes fibrogenic hepatic stellate cells and sensitizes for selective inhibition by mitotropic doxorubicin. J Cell Mol Med. 2018 Apr;22(4):2210-2219. doi: 10.1111/jcmm.13501. Epub 2018 Feb 4.  
Ewald AJ. 2018. Metastasis inside-out: dissemination of cancer cell clusters with inverted polarity. EMBO J. 2018 Apr 3;37(7). pii: e99144. doi: 10.15252/embj.201899144. Epub 2018 Mar 9. No abstract available. PMID:29523585  
Sisk, J.M., M.B. Frieman and C.E. Machamer. 2018. Coronavirus S protein-induced fusion is blocked prior to hemifusion by Abl kinase inhibitors. J. Gen. Virol., Mar 20. doi: 10.1099/jgv.0.001047. [Epub ahead of print]
Gilbert, C.E., E. Sztul and C.E. Machamer. 2018. Commonly used trafficking blocks disrupt ARF1 activation and the localization and function of specific Golgi proteins. Molec. Biol. Cell, E17-11-0622. doi: 10.1091/mbc.E17-11-0622. [Epub ahead of print]  
Edwards M, Cai H, Abubaker-Sharif  B, Long Y, Lampert T, and Devreotes PN. 2018. Insight from the maximal activation of the signal transduction excitable network in Dictyostelium discoideumProc Natl Acad Sci U S A. 2018 Apr 17;115(16):E3722-E3730. doi: 10.1073/pnas.1710480115. Epub 2018 Mar 30.
Neumann NM, Perrone MC, Veldhuis JH, Huebner RJ, Zhan H, Devreotes PN, Brodland GW, and Ewald AJ. 2018. Coordination of receptor tyrosine kinase signaling and interfacial tension dynamics drives radial intercalation and tube elongation. Dev Cell Apr 9;45(1):67-82.e6. doi: 10.1016/j.devcel.2018.03.11.  
McDonald NALind ALSmith SELi RGould KL. Nanoscale architecture of the Schizosaccharomyces pombecontractile ring. Elife. 2017 Sep 15; 6. pii: e28865. doi: 10.7554/eLife.28865.  
Jin Zhu, Hung-Ji Tsai, Molly R. Gordon, Rong Li. Cellular Stress Associated with Aneuploidy; Dev Cell. 2018 Feb 26;44(4):420-431. doi: 10.1016/j.devcel.2018.02.002.