Welcome to the Department of Cell Biology at Johns Hopkins University School of Medicine… More
New Mechanisms in Cell Biology
Dedication of the Isaac Morris Hay and Lucille Elizabeth Hay Professorship… More
Outreach Programs in the Department of Cell Biology… More
Recent News
Updates and news from our department.
Recent Publications
Our latest research and discoveries.
Spear, E.D. and Michaelis, S. (2025) Mammalian Zinc Metalloprotease ZMPSTE24 and Yeast Ste24, Chapter 76. Rawlings – Vol. 1 – Handbook of Proteolytic Enzymes, 4e: Metallopeptidases, Elsevier (In Press)
Odinammadu KO, Shilagardi K, Tuminelli K, Judge DP, Gordon LB, Michaelis S (2023).The farnesyl transferase inhibitor (FTI) lonafarnib improves nuclear morphology in ZMPSTE24-deficient fibroblasts from patients with the progeroid disorder MAD-B. Nucleus. Dec;14(1):2288476. doi: 10.1080/19491034.2023.2288476. Epub 2023 Dec 5. PMID: 38050983; PMCID: PMC10730222
Worman H.J. and Michaelis S. (2023) Prelamin A and ZMPSTE24 in premature and physiological aging. Nucleus. Dec;14(1):2270345. doi: 10.1080/19491034.2023.2270345. Epub 2023 Oct 26. PMID: 37885131; PMCID: PMC10730219
Wang, W., Lu, J., Yang WC, Spear ED, Michaelis S., Matunis M.J. (2023) Analysis of a degron-containing reporter protein GFP-CL1 reveals a role for SUMO1 in cytosolic protein quality control. J Biol Chem. 2023 Feb;299(2):102851. doi: 10.1016/j.jbc.2022.102851. Epub 2022 Dec 29. PMID: 36587767; PMCID: PMC9898758
Featured Research
Catching neurons in action: molecular mechanisms of synaptic transmission and plasticity (Watanabe Lab)
Neurons communicate with each other...