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Welcome to the Department of Cell Biology at Johns Hopkins University School of Medicine… More

New Mechanisms in Cell Biology

Dedication of the Isaac Morris Hay and Lucille Elizabeth Hay Professorship… More

Outreach Programs in the Department of Cell Biology… More

Recent News

Updates and news from our department.

Congratulations to Arisa Ikeda (Sesaki Lab) for winning the Helen B. Taussig Young Investigators’ Day Award!

Congratulations to Arisa Ikeda (Sesaki Lab) for winning the Helen B. Taussig Young Investigators’ Day Award!

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Congratulations to Yiyan Lin (Devreotes Lab) for winning the 2025 David Yue Young Investigators’ Day Award!

Congratulations to Yiyan Lin (Devreotes Lab) for winning the 2025 David Yue Young Investigators’ Day Award!

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Upcoming Events

Seminars and events. Know what’s coming.

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Recent Publications

Our latest research and discoveries.

Spear, E.D. and Michaelis, S. (2025) Mammalian Zinc Metalloprotease ZMPSTE24 and Yeast Ste24, Chapter 76.  Rawlings – Vol. 1 – Handbook of Proteolytic Enzymes, 4e: Metallopeptidases, Elsevier (In Press)

Odinammadu KO, Shilagardi K, Tuminelli K, Judge DP, Gordon LB, Michaelis S (2023).The farnesyl transferase inhibitor (FTI) lonafarnib improves nuclear morphology in ZMPSTE24-deficient fibroblasts from patients with the progeroid disorder MAD-B. Nucleus. Dec;14(1):2288476. doi: 10.1080/19491034.2023.2288476. Epub 2023 Dec 5. PMID: 38050983; PMCID: PMC10730222

Worman H.J. and Michaelis S. (2023) Prelamin A and ZMPSTE24 in premature and physiological aging. Nucleus. Dec;14(1):2270345. doi: 10.1080/19491034.2023.2270345. Epub 2023 Oct 26. PMID: 37885131; PMCID: PMC10730219

Wang, W., Lu, J., Yang WC, Spear ED, Michaelis S., Matunis M.J. (2023) Analysis of a degron-containing reporter protein GFP-CL1 reveals a role for SUMO1 in cytosolic protein quality control. J Biol Chem. 2023 Feb;299(2):102851. doi: 10.1016/j.jbc.2022.102851. Epub 2022 Dec 29. PMID: 36587767; PMCID: PMC9898758

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